Targeting Prostate Carcinoma by G3-C12 Peptide Conjugated N-(2-Hydroxypropyl)methacrylamide Copolymers
Abstract
Prostate carcinoma is the second leading cause of cancer-related deaths. Increased expression of membrane-bound galectin-3 by prostate carcinoma cell has been found to correlate with more poorly differentiated and increased metastatic potential. In the present study, different amount of galectin-3-binding peptide, G3-C12 (the sequence ANTPCGPYTHDCPVKR), was attached to N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers as targeting moiety. The...
Paper Details
Title
Targeting Prostate Carcinoma by G3-C12 Peptide Conjugated N-(2-Hydroxypropyl)methacrylamide Copolymers
Published Date
Jun 30, 2014
Journal
Volume
11
Issue
10
Pages
3251 - 3260
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