Effect of Duct Ligation on Rat Submandibular Salivary Gland.

The effect of duct ligation on the submandibular salivary gland was studied in rats. Submandibular gland ducts were ligated, and the location of peroxidase activity was examined 2, 4 and 8 weeks later.After 2 weeks secretory granules in the acinar cells were markedly decreased and the substructure was visible in the granules of some acinar cells.After 4 weeks the acini consisted of two types of cells. One type contained granules which were...