Unexpected pro-injury effect of propofol on vascular smooth muscle cells with increased oxidative stress*

Propofol is a widely used intravenous anesthetic agent with antioxidant properties. However, the effect of propofol on reactive oxygen species-induced injury in vascular smooth muscle cells is still unknown. In this study, the authors determined the effect of propofol on hydrogen peroxide-induced injury in vascular smooth muscle cells and the potential molecular mechanisms involved.Prospective cell and animal study.University research...