Inhibitors of c-Jun N-terminal kinases: an update.

Volume: 58, Issue: 1, Pages: 72 - 95
Published: Jan 8, 2015
Abstract
The c-Jun N-terminal kinases (JNKs) are serine/threonine kinases implicated in the pathogenesis of various diseases. Recent advances in the development of novel inhibitors of JNKs will be reviewed. Significant progress in the design of JNK inhibitors displaying selectivity versus other kinases has been achieved within the past 4 years. However, the development of isoform selective JNK inhibitors is still an open...
Paper Details
Title
Inhibitors of c-Jun N-terminal kinases: an update.
Published Date
Jan 8, 2015
Volume
58
Issue
1
Pages
72 - 95
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