Roux-en-Y Gastric Bypass Surgery Suppresses Hepatic Gluconeogenesis and Increases Intestinal Gluconeogenesis in a T2DM Rat Model

Yong Yan; Zhou Zhou; Fanzhi Kong; Suibin Feng; Xuzhong Li; Yanhua Sha; Guangjun Zhang; Haijun Liu; Haiqing Zhang; Shiguang Wang; Cheng Hu; Xueli Zhang

doi:https://doi.org/10.1007/s11695-016-2157-5

doi.org/10.1007/s11695-016-2157-5

Roux-en-Y Gastric Bypass Surgery Suppresses Hepatic Gluconeogenesis and Increases Intestinal Gluconeogenesis in a T2DM Rat Model

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..., Xueli Zhang

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Obesity Surgery2.90

Volume: 26, Issue: 11, Pages: 2683 - 2690

Published: Apr 1, 2016

Abstract

Roux-en-Y gastric bypass (RYGB) is an effective surgical treatment for type 2 diabetes mellitus (T2DM). The present study aimed to investigate the effects of RYGB on glucose homeostasis, lipid metabolism, and intestinal morphological adaption, as well as hepatic and intestinal gluconeogenesis. Twenty adult male T2DM rats induced by high-fat diet and low dose of streptozotocin were randomly divided into sham and RYGB groups. The parameters of...

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Paper Details

Title

Roux-en-Y Gastric Bypass Surgery Suppresses Hepatic Gluconeogenesis and Increases Intestinal Gluconeogenesis in a T2DM Rat Model

DOI

doi.org/10.1007/s11695-016-2157-5

Published Date

Apr 1, 2016

Journal

Obesity Surgery

Volume

26

Issue

11

Pages

2683 - 2690

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