Mosaic pattern of Cre recombinase expression in cochlear outer hair cells of the Brn3.1 Cre mouse

Volume: 26, Issue: 6, Pages: 309 - 313
Published: Apr 15, 2015
Abstract
The Brn3.1 gene encodes for the protein Brn3.1, which is a member of the POU-IV class of transcription factors. Mutation leads to nonsyndromic human progressive hearing loss (DFNA15). To investigate the suitability of the Brn3.1 promoter for Cre recombinase-induced genetic recombination in cochlear hair cells, we established a transgenic Brn3.1 Cre mouse. This mouse line was crossbred with floxed ROSA26lacZ and ROSA26eYFP reporter mice. The...
Paper Details
Title
Mosaic pattern of Cre recombinase expression in cochlear outer hair cells of the Brn3.1 Cre mouse
Published Date
Apr 15, 2015
Journal
Volume
26
Issue
6
Pages
309 - 313
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