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Impact of parity on bone metabolism throughout the reproductive cycle in sows

Published on Oct 1, 2016in Animal2.03
· DOI :10.1017/S1751731116000471
M. M. J. van Riet4
Estimated H-index: 4
,
Sam Millet16
Estimated H-index: 16
+ 5 AuthorsGeert Janssens27
Estimated H-index: 27
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Abstract
Bone metabolism fluctuates throughout the reproductive cycle of sows to enable foetal growth and milk production. Although increased bone mineralisation is conceivable in sows during reproduction, a study of mineralisation in function of parity has not been performed. This study evaluated the fluctuations of markers for bone metabolism in primiparous and multiparous sows throughout a reproductive cycle. The experiment included ten multiparous and five primiparous commercial hybrid sows from one herd. The sows were monitored for one reproductive cycle and fed according to commercial dietary standards. Blood samples were taken in the morning before feeding at fixed time intervals before (day -5) and during gestation (insemination (day 0), 21, 42, 63, 84), around parturition (day 108, 112, parturition (115), 118), and during lactation (day 122, 129, 143). Serum osteocalcin (OC) concentration increased in early and mid-gestation (P=0.002) and decreased at the end of gestation (P=0.001), whereas crosslaps (CTX) concentration decreased during early and mid-gestation (P=0.002) and increased towards the end of gestation (P=0.001). Towards the end of lactation serum levels of both markers increased (P=0.007 and 0.013, respectively). For hydroxyproline (HYP) no significant fluctuation in function of the reproductive cycle was detected. Matrix metalloproteinase 2 (MMP2) concentration increased towards parturition for both primiparous and multiparous sows (P=0.001), whereas during lactation no significant fluctuations in function of the reproductive cycle were found. A parity effect was found for OC and CTX (P<0.010), but not for the other markers. These results demonstrate that bone metabolism differed between primiparous and multiparous sows, although in both groups a similar fluctuation throughout the reproductive cycle was observed.
  • References (37)
  • Citations (2)
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References37
Newest
Published on Jan 1, 2016in Journal of Bone and Mineral Research5.71
Dennis T. Villareal44
Estimated H-index: 44
(WashU: Washington University in St. Louis),
Luigi Fontana48
Estimated H-index: 48
(WashU: Washington University in St. Louis)
+ 9 AuthorsMegan Huang3
Estimated H-index: 3
(Durham University)
Although caloric restriction (CR) could delay biologic aging in humans, it is unclear if this would occur at the cost of significant bone loss. We evaluated the effect of prolonged CR on bone metabolism and bone mineral density (BMD) in healthy younger adults. Two-hundred eighteen non-obese (body mass index [BMI] 25.1 ± 1.7 kg/m2), younger (age 37.9 ± 7.2 years) adults were randomly assigned to 25% CR (CR group, n = 143) or ad libitum (AL group, n = 75) for 2 years. Main outcomes were BMD and ma...
Published on Mar 1, 2014in Animal Reproduction Science1.82
An Cools9
Estimated H-index: 9
(UGent: Ghent University),
Dominiek Maes42
Estimated H-index: 42
(UGent: Ghent University)
+ 4 AuthorsGeert Janssens27
Estimated H-index: 27
(UGent: Ghent University)
To overcome negative energy balance during the peripartal period of sows, an ad libitum feeding strategy (ADLIB) as alternative for commonly used restricted feeding (STANDARD, on average 3kg feed/day) was evaluated. Plasma metabolites and thyroid hormones, change of back fat thickness (BF), reproductive traits, and piglet performance were monitored. Voluntary feed intake of ADLIB sows declined at farrowing but was still more than twice the amount of what was offered to STANDARD sows. Consequentl...
Published on Oct 1, 2013in Animal Frontiers
Robert D. Goodband41
Estimated H-index: 41
(KSU: Kansas State University),
Michael D. Tokach39
Estimated H-index: 39
(KSU: Kansas State University)
+ 3 AuthorsJoel M. DeRouchey21
Estimated H-index: 21
(KSU: Kansas State University)
Published on Sep 30, 2013in International Journal of Molecular Sciences4.18
Ashish Ranjan Sharma14
Estimated H-index: 14
,
Supriya Jagga3
Estimated H-index: 3
+ 1 AuthorsJu-Suk Nam14
Estimated H-index: 14
Osteoarthritis (OA) is a common debilitating joint disorder, affecting large sections of the population with significant disability and impaired quality of life. During OA, functional units of joints comprising cartilage and subchondral bone undergo uncontrolled catabolic and anabolic remodeling processes to adapt to local biochemical and biological signals. Changes in cartilage and subchondral bone are not merely secondary manifestations of OA but are active components of the disease, contribut...
Published on Sep 1, 2013in Livestock Science1.38
M. M. J. van Riet4
Estimated H-index: 4
(UGent: Ghent University),
Sam Millet16
Estimated H-index: 16
+ 1 AuthorsGeert Janssens27
Estimated H-index: 27
(UGent: Ghent University)
Abstract Sow lameness is a multifactorial condition which is mostly related to disturbances in the processes of bone remodelling, cartilage metabolism, and horn production. This review discusses how bone, articular cartilage and horn are affected by diet composition, particularly vitamins and minerals. For bone remodelling, the role of carbohydrates, proteins, and amino acids is uncertain. The macrominerals Ca and P are extremely important, as is vitamin D. Magnesium may be as important as Ca an...
Published on Aug 1, 2013in Veterinary Journal1.92
Reiichiro Sato9
Estimated H-index: 9
(Azabu University),
Ken Onda7
Estimated H-index: 7
(Azabu University)
+ 6 AuthorsYasunori Wada7
Estimated H-index: 7
(Azabu University)
Abstract Various biochemical markers help to evaluate the state of bone turnover in humans and could be used during the peri-parturient period in dairy cows when calcium (Ca) metabolism changes dramatically. To investigate this, the peri-partum characteristics of serum bone-specific alkaline phosphatase (BAP) and urinary deoxypyridinoline (DPD) were investigated. Both serum BAP activity and urinary DPD concentrations were increased and demonstrated wide variability in younger animals, and these ...
Published on Jul 24, 2012in Nutrients4.17
Carmen M. Donangelo29
Estimated H-index: 29
(University of the Republic),
Janet C. King48
Estimated H-index: 48
(Children's Hospital Oakland Research Institute)
Zinc plays critical roles during embryogenesis, fetal growth, and milk secretion, which increase the zinc need for pregnancy and lactation. Increased needs can be met by increasing the dietary zinc intake, along with making homeostatic adjustments in zinc utilization. Potential homeostatic adjustments include changes in circulating zinc, increased zinc absorption, decreased zinc losses, and changes in whole body zinc kinetics. Although severe zinc deficiency during pregnancy has devastating effe...
Published on Oct 1, 2011in Research in Veterinary Science1.75
Reiichiro Sato9
Estimated H-index: 9
(Azabu University),
Ken Onda7
Estimated H-index: 7
(Azabu University)
+ 3 AuthorsYasunori Wada7
Estimated H-index: 7
(Azabu University)
Abstract We evaluated age-related changes in serum osteocalcin concentrations in non-periparturient cows and variations in serum osteocalcin concentration in periparturient primiparous and multiparous cows. The serum osteocalcin levels were evaluated in 144 non-periparturient Holstein dairy cows aged 11 days to 10 years; these levels were the highest in the youngest cows, appeared to steadily decrease with age until the time of the first calving, and were subsequently maintained at low levels. B...
Published on Jan 1, 2010in Journal of Animal Science1.70
Charlotte Lauridsen25
Estimated H-index: 25
(AU: Aarhus University),
Ulrich Halekoh16
Estimated H-index: 16
(AU: Aarhus University)
+ 1 AuthorsSøren Krogh Jensen33
Estimated H-index: 33
(AU: Aarhus University)
In swine nutrition, little is known about the vitamin D requirements for reproductive processes and bone health. Consequently, the vitamin D recom- mendation for sows during gestation and lactation is not based on scientific reports. The current study was undertaken to obtain information on the dose-response pattern of 2 vitamin D sources, the commonly used cholecalciferol, called vitamin D 3, and a newly developed Hy·D product (25-hydroxycholecalciferol). In Exp. 1, a total of 160 gilts were ra...
Published on Jan 1, 2010in Bone4.36
Indira Prasadam16
Estimated H-index: 16
(QUT: Queensland University of Technology),
Thor Friis15
Estimated H-index: 15
(QUT: Queensland University of Technology)
+ 3 AuthorsYin Xiao46
Estimated H-index: 46
(QUT: Queensland University of Technology)
Abstract Osteoarthritic subchondral bone is characterized by abnormal bone density and enhanced production of bone turnover markers, an indication of osteoblast dysfunction. Several studies have proposed that pathological changes in articular cartilage influence the subchondral bone changes, which are typical of the progression of osteoarthritis; however, direct evidence of this has yet to be reported. The aim of the present study was to investigate what effects articular cartilage cells, isolat...
Cited By2
Newest
Published on May 1, 2019in Journal of Animal Physiology and Animal Nutrition1.70
Miriam Mj van Riet2
Estimated H-index: 2
(UGent: Ghent University),
Sam Millet16
Estimated H-index: 16
+ 2 AuthorsGeert Janssens27
Estimated H-index: 27
(UGent: Ghent University)
DNA methylation is an important epigenetic strategy for embryo development and survival. The one-carbon metabolism can be disturbed by inadequate provision of dietary methyl donors. Because of the continuous selection for larger litters, it is relevant to explore if highly prolific sows might encounter periods of methyl donor deficiency throughout their reproductive cycles. This study, therefore, assesses the fluctuation(s) in methylation potential (MP) and aims to link possible methyl donor def...
Published on Dec 1, 2018in Journal of Animal Physiology and Animal Nutrition1.70
Christina M. Schmidt (UA: University of Alabama), Lee I. Chiba (UA: University of Alabama), Wendy R. Hood (UA: University of Alabama)