Rapamycin Blocks Induction of the Thermogenic Program in White Adipose Tissue

Volume: 65, Issue: 4, Pages: 927 - 941
Published: Feb 8, 2016
Abstract
Rapamycin extends life span in mice, yet paradoxically causes lipid dysregulation and glucose intolerance through mechanisms that remain incompletely understood. Whole-body energy balance can be influenced by beige/brite adipocytes, which are inducible by cold and other stimuli via β-adrenergic signaling in white adipose depots. Induction of beige adipocytes is considered a promising strategy to combat obesity because of their ability to...
Paper Details
Title
Rapamycin Blocks Induction of the Thermogenic Program in White Adipose Tissue
Published Date
Feb 8, 2016
Journal
Volume
65
Issue
4
Pages
927 - 941
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