Cardioprotective actions of Notch1 against myocardial infarction via LKB1-dependent AMPK signaling pathway

Volume: 108, Pages: 47 - 57
Published: May 1, 2016
Abstract
AMP-activated protein kinase (AMPK) signaling pathway plays a pivotal role in intracellular adaptation to energy stress during myocardial ischemia. Notch1 signaling in the adult myocardium is also activated in response to ischemic stress. However, the relationship between Notch1 and AMPK signaling pathways during ischemia remains unclear. We hypothesize that Notch1 as an adaptive signaling pathway protects the heart from ischemic injury via...
Paper Details
Title
Cardioprotective actions of Notch1 against myocardial infarction via LKB1-dependent AMPK signaling pathway
Published Date
May 1, 2016
Volume
108
Pages
47 - 57
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