Damnacanthal and its nanoformulation exhibit anti-cancer activity via cyclin D1 down-regulation
Abstract
Damnacanthal is an anthraquinone isolated from the root of Morinda citrifolia L. (noni), and it exhibits many pharmacological properties, including anti-cancer activity. Damnacanthal targets several signal transduction proteins related to cell growth inhibition or apoptosis. However, the molecular mechanisms by which damnacanthal affects cell cycle regulation have not been elucidated in detail.Cyclin D1 is an important regulatory protein in cell...
Paper Details
Title
Damnacanthal and its nanoformulation exhibit anti-cancer activity via cyclin D1 down-regulation
Published Date
May 1, 2016
Journal
Volume
152
Pages
60 - 66
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