Loss of Mitochondrial Function Impairs Lysosomes.

Volume: 291, Issue: 19, Pages: 10263 - 10276
Published: May 6, 2016
Abstract
Alterations in mitochondrial function, as observed in neurodegenerative diseases, lead to disrupted energy metabolism and production of damaging reactive oxygen species. Here, we demonstrate that mitochondrial dysfunction also disrupts the structure and function of lysosomes, the main degradation and recycling organelle. Specifically, inhibition of mitochondrial function, following deletion of the mitochondrial protein AIF, OPA1, or PINK1, as...
Paper Details
Title
Loss of Mitochondrial Function Impairs Lysosomes.
Published Date
May 6, 2016
Volume
291
Issue
19
Pages
10263 - 10276
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.