Mechanistic basis of MAGUK-organized complexes in synaptic development and signalling
Abstract
Membrane-associated guanylate kinases (MAGUKs) are a family of scaffold proteins that are highly enriched in synapses and are responsible for organizing the numerous protein complexes required for synaptic development and plasticity. Mutations in genes encoding MAGUKs and their interacting proteins can cause a broad spectrum of human psychiatric disorders. Here, we review MAGUK-mediated synaptic protein complex formation and regulation by...
Paper Details
Title
Mechanistic basis of MAGUK-organized complexes in synaptic development and signalling
Published Date
Apr 1, 2016
Journal
Volume
17
Issue
4
Pages
209 - 223
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