Ultrasensitive caspase-3 activity detection using an electrochemical biosensor engineered by gold nanoparticle functionalized MCM-41: Its application during stem cell differentiation

Caspase-3 has a critical role in the apoptotic process and hematopoietic stem cell differentiation and its detection has been a major focus of research interest and attention. In this study, an ultrasensitive novel electrochemical biosensor for convenient, sensitive and selective detection of caspase-3 activity was developed. Gold nanoparticles functionalized silica-based mesoporous material (MCM-41) modified glassy carbon electrode was designed...