Effect of cannabis on glutamate signalling in the brain: A systematic review of human and animal evidence.

Volume: 64, Pages: 359 - 381
Published: May 1, 2016
Abstract
Use of cannabis or delta-9-tetrahydrocannabinol (Δ9-THC), its main psychoactive ingredient, is associated with psychotic symptoms or disorder. However, the neurochemical mechanism that may underlie this psychotomimetic effect is poorly understood. Although dopaminergic dysfunction is generally recognized as the final common pathway in psychosis, evidence of the effects of Δ9-THC or cannabis use on dopaminergic measures in the brain is equivocal....
Paper Details
Title
Effect of cannabis on glutamate signalling in the brain: A systematic review of human and animal evidence.
Published Date
May 1, 2016
Volume
64
Pages
359 - 381
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