The Effect of Sustained Inflammation on Hepatic Mevalonate Pathway Results in Hyperglycemia
Abstract
Control of plasma glucose level is essential to organismal survival. Sustained inflammation has been implicated in control of glucose homeostasis in cases of infection, obesity, and type 2 diabetes; however, the precise role of inflammation in these complex disease states remains poorly understood. Here, we find that sustained inflammation results in elevated plasma glucose due to increased hepatic glucose production. We find that sustained...
Paper Details
Title
The Effect of Sustained Inflammation on Hepatic Mevalonate Pathway Results in Hyperglycemia
Published Date
Apr 1, 2016
Journal
Volume
165
Issue
2
Pages
343 - 356
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