Evaluating statistical characteristics of biomarker-guided trial designs

Stratified or personalized medicine is a rapidly growing area of research and has attracted much attention in recent years not only in the field of oncology but also in other diseases. The aim of stratified medicine is to tailor the treatment given to a patient according to one or more personal characteristics. These characteristics can be demographic such as age or gender, or biological such as a genetic or other biomarker. Prior to utilising a...