The Effect of Intravenous Anesthetics on Vascular Function of Arteriovenous Fistula in Normal and Hyperglycemia Rats

Background. Infusion of propofol often causes significant vasodilation, and followed by drop of blood pressure. However, the exact under1ying mechanisms of this phenomenon remain unc1ear. This study investigated the molecular mechanisms of propofol-induced vasodilation. Objectives & Methods. Changes in isometric tension of pre-contracted aortic segments isolated from control and rats with diabetes mellitus were recorded following cumulative...