doi.org/10.1016/j.cbi.2016.03.015
Original paper

Chrysin, a PPAR-γ agonist improves myocardial injury in diabetic rats through inhibiting AGE-RAGE mediated oxidative stress and inflammation

..., Dharamvir Singh Arya
36
Chemico-Biological Interactions4.70
Volume: 250, Pages: 59 - 67
Published: Apr 1, 2016
Abstract
AGE-RAGE interaction mediated oxidative stress and inflammation is the key mechanism involved in the pathogenesis of cardiovascular disease in diabetes. Inhibition of AGE-RAGE axis by several PPAR-γ agonists has shown positive results in ameliorating cardio-metabolic disease conditions. Chrysin, a natural flavonoid has shown to possess PPAR-γ agonist activity along with antioxidant and anti-inflammatory effect. Therefore, the present study was...
Paper Fields
Paper Details
Title
Chrysin, a PPAR-γ agonist improves myocardial injury in diabetic rats through inhibiting AGE-RAGE mediated oxidative stress and inflammation
DOI
doi.org/10.1016/j.cbi.2016.03.015
Published Date
Apr 1, 2016
Journal
Chemico-Biological Interactions
Volume
250
Pages
59 - 67
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