Autoantibody Production in Cancer--The Humoral Immune Response toward Autologous Antigens in Cancer Patients.
Abstract
A link between autoimmune responses and cancer via autoantibodies was first described in the 1950s. Since, autoantibodies have been studied for their potential use as cancer biomarkers, however the exact causes of their production remain to be elucidated. This review summarizes current theories of the causes of autoantibody production in cancer, namely: 1) defects in tolerance and inflammation, 2) changes in protein expression levels, 3) altered...
Paper Details
Title
Autoantibody Production in Cancer--The Humoral Immune Response toward Autologous Antigens in Cancer Patients.
Published Date
May 1, 2016
Journal
Volume
15
Issue
5
Pages
477 - 483
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Notes
History