Convertible visceral fat as a therapeutic target to curb obesity

Current therapies for obesity have limited efficacy and may be associated with substantial adverse effects. Cinti and colleagues discuss the conversion of white fat to brown, thermogenic fat as a potential strategy to curb obesity. Adipocyte conversion could be particularly important in the visceral compartment, as fat in this region is associated with morbidity but is also particularly prone to transdifferentiation. New therapeutic and...