To PSA or not to PSA? Still a question for men with a family history of prostate cancer

Family history (FH) has long been known to increase a man's risk of developing prostate cancer (PCa); there is an approximately twofold increased risk with an affected father and a threefold increased risk with an affected brother 1. Furthermore, FH may increase the risk of more aggressive disease for family members, although results of studies in the PSA screening era have been inconsistent 2, 3. Using FH as a risk factor, the present analysis...