The first decade of estrogen receptor cistromics in breast cancer
Abstract
The advent of genome-wide transcription factor profiling has revolutionized the field of breast cancer research. Estrogen receptor α (ERα), the major drug target in hormone receptor-positive breast cancer, has been known as a key transcriptional regulator in tumor progression for over 30 years. Even though this function of ERα is heavily exploited and widely accepted as an Achilles heel for hormonal breast cancer, only since the last decade we...
Paper Details
Title
The first decade of estrogen receptor cistromics in breast cancer
Published Date
May 1, 2016
Journal
Volume
229
Issue
2
Pages
R43 - R56
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