The heterogeneity of human CD127+ innate lymphoid cells revealed by single-cell RNA sequencing

Volume: 17, Issue: 4, Pages: 451 - 460
Published: Apr 1, 2016
Abstract
Innate lymphoid cells (ILCs) are increasingly appreciated as important participants in homeostasis and inflammation. Substantial plasticity and heterogeneity among ILC populations have been reported. Here we have delineated the heterogeneity of human ILCs through single-cell RNA sequencing of several hundreds of individual tonsil CD127(+) ILCs and natural killer (NK) cells. Unbiased transcriptional clustering revealed four distinct populations,...
Paper Details
Title
The heterogeneity of human CD127+ innate lymphoid cells revealed by single-cell RNA sequencing
Published Date
Apr 1, 2016
Volume
17
Issue
4
Pages
451 - 460
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