Role of Oxidative Stress in Liver Health and Disease

Liver diseases are a worldwide medical problem because the liver is the principal detoxifying organ and maintains metabolic homeostasis. The liver metabolizes various compounds that produce reactive oxygen radicals (ROS). Prooxidants are ROS which can cause tissue liver damage and whose levels may be increased by certain drugs, infection, external exposures, tissue injury, and so forth. Oxidative stress can result from an increase in prooxidant...