Dysfunctional high-density lipoproteins in coronary heart disease: implications for diagnostics and therapy
Abstract
Low plasma levels of high-density lipoprotein (HDL) cholesterol are associated with increased risks of coronary heart disease. HDL mediates cholesterol efflux from macrophages for reverse transport to the liver and elicits many anti-inflammatory and anti-oxidative activities which are potentially anti-atherogenic. Nevertheless, HDL has not been successfully targeted by drugs for prevention or treatment of cardiovascular diseases. One potential...
Paper Details
Title
Dysfunctional high-density lipoproteins in coronary heart disease: implications for diagnostics and therapy
Published Date
Jul 1, 2016
Journal
Volume
173
Pages
30 - 57
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Notes
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