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Cancer statistics in China, 2015

Published on Mar 1, 2016in CA: A Cancer Journal for Clinicians223.68
· DOI :10.3322/caac.21338
Wanqing Chen35
Estimated H-index: 35
,
Rongshou Zheng27
Estimated H-index: 27
+ 6 AuthorsJie He24
Estimated H-index: 24
Cite
Abstract
With increasing incidence and mortality, cancer is the leading cause of death in China and is a major public health problem. Because of China's massive population (1.37 billion), previous national incidence and mortality estimates have been limited to small samples of the population using data from the 1990s or based on a specific year. With high-quality data from an additional number of population-based registries now available through the National Central Cancer Registry of China, the authors analyzed data from 72 local, population-based cancer registries (2009-2011), representing 6.5% of the population, to estimate the number of new cases and cancer deaths for 2015. Data from 22 registries were used for trend analyses (2000-2011). The results indicated that an estimated 4292,000 new cancer cases and 2814,000 cancer deaths would occur in China in 2015, with lung cancer being the most common incident cancer and the leading cause of cancer death. Stomach, esophageal, and liver cancers were also commonly diagnosed and were identified as leading causes of cancer death. Residents of rural areas had significantly higher age-standardized (Segi population) incidence and mortality rates for all cancers combined than urban residents (213.6 per 100,000 vs 191.5 per 100,000 for incidence; 149.0 per 100,000 vs 109.5 per 100,000 for mortality, respectively). For all cancers combined, the incidence rates were stable during 2000 through 2011 for males (+0.2% per year; P = .1), whereas they increased significantly (+2.2% per year; P < .05) among females. In contrast, the mortality rates since 2006 have decreased significantly for both males (−1.4% per year; P < .05) and females (−1.1% per year; P < .05). Many of the estimated cancer cases and deaths can be prevented through reducing the prevalence of risk factors, while increasing the effectiveness of clinical care delivery, particularly for those living in rural areas and in disadvantaged populations. CA Cancer J Clin 2016;66:115–132. © 2016 American Cancer Society.
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  • References (74)
  • Citations (3163)
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References74
Newest
Published on Mar 15, 2016in International Journal of Cancer4.98
Melissa Valdez6
Estimated H-index: 6
(PATH),
Jose Jeronimo34
Estimated H-index: 34
(PATH)
+ 12 AuthorsPing Bai6
Estimated H-index: 6
(Peking Union Medical College)
This study examined the efficacy of the OncoE6™ Cervical Test, careHPV™ and visual inspection with acetic acid (VIA) in identifying women at risk for cervical cancer and their capability to detect incident cervical precancer and cancer at 1-year follow-up. In a population of 7,543 women living in rural China, women provided a self-collected and two clinician-collected specimens and underwent VIA. All screen positive women for any of the tests, a ∼ 10% random sample of test-negative women that un...
Published on Feb 1, 2016in Clinical Endocrinology2.90
Nirmala Pandeya41
Estimated H-index: 41
(UQ: University of Queensland),
Donald S. A. McLeod13
Estimated H-index: 13
(QIMR: QIMR Berghofer Medical Research Institute)
+ 5 AuthorsSusan J. Jordan24
Estimated H-index: 24
(QIMR: QIMR Berghofer Medical Research Institute)
SummaryBackground Thyroid cancer incidence has been increasing worldwide. Some suggest greater ascertainment of indolent tumours is the only driver, but others suggest there has been a true increase. Increases in Australia appear to have been among the largest in the world, so we investigated incidence trends in the Australian state of Queensland to help understand reasons for the rise. Methods Thyroid cancers diagnoses in Queensland 1982–2008 were ascertained from the Queensland Cancer Registry...
Published on Dec 1, 2015in Chinese Journal of Cancer
Shen Chen1
Estimated H-index: 1
(SYSU: Sun Yat-sen University),
Jinhong Zhu15
Estimated H-index: 15
(HMU: Harbin Medical University)
+ 5 AuthorsWei Hua Jia39
Estimated H-index: 39
(SYSU: Sun Yat-sen University)
Polymorphisms in DNA repair genes may alter DNA repair capacity and, consequently, lead to genetic instability and carcinogenesis. Several studies have investigated the association of the Asp312Asn and Lys751Gln polymorphisms in the xeroderma pigmentosum complementation group D (XPD) gene with the risk of non-Hodgkin’s lymphoma (NHL), but the conclusions have been inconsistent. Therefore, we performed this meta-analysis to more precisely estimate these relationships. A systematic literature sear...
Published on Oct 1, 2015in The Lancet59.10
Zhengming Chen46
Estimated H-index: 46
(Clinical Trial Service Unit),
Richard Peto161
Estimated H-index: 161
(Clinical Trial Service Unit)
+ 16 AuthorsGarry Lancaster1
Estimated H-index: 1
(Clinical Trial Service Unit)
Summary Background Chinese men now smoke more than a third of the world's cigarettes, following a large increase in urban then rural usage. Conversely, Chinese women now smoke far less than in previous generations. We assess the oppositely changing effects of tobacco on male and female mortality. Methods Two nationwide prospective studies 15 years apart recruited 220 000 men in about 1991 at ages 40–79 years (first study) and 210 000 men and 300 000 women in about 2006 at ages 35–74 years (secon...
Published on Dec 1, 2015in International Journal for Equity in Health2.47
Chunhui Li2
Estimated H-index: 2
(WHU: Wuhan University),
Chuanhua Yu34
Estimated H-index: 34
(WHU: Wuhan University),
Peigang Wang9
Estimated H-index: 9
(WHU: Wuhan University)
Background Breast cancer is the most common cause of cancer—related death among women. In this paper, we studied the variations in the trends of Chinese female breast cancer mortality by age, period and cohort from 1990 to 2009.
Published on Sep 1, 2015in Lancet Oncology35.39
Richard Sullivan28
Estimated H-index: 28
(HealthPartners),
Olusegun Isaac Alatise11
Estimated H-index: 11
(OAU: Obafemi Awolowo University)
+ 40 AuthorsAnil D'Cruz24
Estimated H-index: 24
(ACTREC: Tata Memorial Hospital)
Summary Surgery is essential for global cancer care in all resource settings. Of the 15·2 million new cases of cancer in 2015, over 80% of cases will need surgery, some several times. By 2030, we estimate that annually 45 million surgical procedures will be needed worldwide. Yet, less than 25% of patients with cancer worldwide actually get safe, affordable, or timely surgery. This Commission on global cancer surgery, building on Global Surgery 2030, has examined the state of global cancer surger...
Published on Sep 1, 2015in Cancer6.10
Qunying Hong5
Estimated H-index: 5
,
Guoming Wu1
Estimated H-index: 1
+ 11 AuthorsQi Wang2
Estimated H-index: 2
Lung cancer is the leading cause of cancer-related death worldwide. In China, the incidence of lung cancer has grown rapidly, resulting in a large social and economic burden. Several researchers have devoted their studies to lung cancer and have demonstrated that there are many risk factors for lung cancer in China, including tobacco use, environmental pollution, food, genetics, and chronic obstructive pulmonary disease. However, the lung cancer incidence is still growing rapidly in China, and t...
Published on Sep 1, 2015in Cancer6.10
Electra D. Paskett56
Estimated H-index: 56
(OSU: Ohio State University),
Brittany M. Bernardo4
Estimated H-index: 4
(OSU: Ohio State University),
Fadlo R. Khuri79
Estimated H-index: 79
(Emory University)
Published on Sep 1, 2015in Cancer6.10
Zhengming Chen46
Estimated H-index: 46
(Clinical Trial Service Unit),
Richard Peto161
Estimated H-index: 161
(Clinical Trial Service Unit)
+ 9 AuthorsJunshi Chen19
Estimated H-index: 19
(CFS: Center for Food Safety)
BACKGROUND In China, cigarette consumption has increased substantially since the 1980s, almost exclusively in men. This study was aimed at assessing the emerging cancer risks.
Cited By3163
Newest
Published on Jan 1, 2020in Redox biology7.79
Sen Wang (Nanjing Medical University), Zheng Chen10
Estimated H-index: 10
(UM: University of Miami)
+ 9 AuthorsAlexander Zaika1
Estimated H-index: 1
(UM: University of Miami)
Abstract Background Helicobacter pylori (H. pylori) infection is the main risk factor for gastric cancer. The role of antioxidant enzyme peroxiredoxin 2 (PRDX2) in gastric tumorigenesis remains unknown. In vitro (AGS and SNU1 cell lines) and in vivo mouse models were utilized to investigate the role of PRDX2 in response to H. pylori infection (7.13, J166 or PMSS1 strain). We detected high levels of PRDX2 expression in gastric cancer tissues. Gastric cancer patients with high expression levels of...
Published on 2020in Journal of Gynecologic Oncology2.91
Haoran Li1
Estimated H-index: 1
(Fudan University),
Yangyang Pang (University of Medicine and Health Sciences), XiCheng13
Estimated H-index: 13
(Fudan University)
Published on Jan 1, 2020in Journal of Gynecologic Oncology2.91
Xiaofeng Lv6
Estimated H-index: 6
(Zhengzhou University),
Shi‐Hong Cui1
Estimated H-index: 1
(Zhengzhou University)
+ 1 AuthorsChen‐Chen Ren1
Estimated H-index: 1
(Zhengzhou University)
Bin Li (Lanzhou University), Yu-Qi Meng (Lanzhou University)+ 4 AuthorsShao-Bo Zhang (Lanzhou University)
AbstractThe long-term prognosis of patients with lung cancer remains poor and thus it is imminent to further elucidate the molecular mechanism for the oncogenesis of lung cancer. In this study, we ...
Wangwang Chen (Nanjing Medical University), Jian Xiao (Nanjing Medical University)+ 7 AuthorsZekuan Xu13
Estimated H-index: 13
(Nanjing Medical University)
AbstractAstaxanthin, a Xanthophyll carotenoid, has strong antioxidant properties. Some studies have shown the effectiveness of this compound on the prevention and treatment of cancer. Therefore, the aim of this study was to evaluate the effects of astaxanthin on induction of apoptosis and antioxidant activity in the LS-180 cell line. In this experimental study, after the treatment of LS-180 50, 100 and 150 μm of Astaxanthin for 24 h, the expression levels of Bax, Bcl2 and Caspase3 genes were inv...
Published on May 13, 2019in Artificial Cells Nanomedicine and Biotechnology4.46
AbstractObjective: Our study aims to investigate the effect of arsenic trioxide (As2O3) on proliferation and apoptosis of Tca8113 tongue squamous carcinoma cells.Methods: Cell proliferation and the expression of Id-1 mRNA in Tca8113 cells after treatment with different concentrations of As2O3 were detected by MTT and qRT-PCR, respectively. The expression of Id-1, cell proliferation and apoptosis in Id-1 silencing Tca8113 cells were detected by qRT-PCR, Western blot, MTT and flow cytometry, respe...
Published on Dec 4, 2019in Artificial Cells Nanomedicine and Biotechnology4.46
Xiantao Sun (Zhengzhou University), Yang Bai (Zhengzhou University)+ 3 AuthorsGuixian Wang (Zhengzhou University)
AbstractColon cancer, also known as colorectal carcinoma (CRC), remains to be one of the most mainsprings of cancer-produced deaths entire world. We planned to grab the role and possible biological cause of a long noncoding RNA, namely, small nucleolar RNA host gene 15 (SNHG15), in CRC. The mRNA level of SNHG15 in CRC tissues and cells was detected, followed by investigating the impacts of the depression of SNHG15 on CRC cell proliferation (viability and colony-forming), apoptosis, migration, an...
Published on Jan 10, 2019in Cellular & Molecular Biology Letters3.37
Lin Xie5
Estimated H-index: 5
(Kunming Medical University),
Yajuan Chen3
Estimated H-index: 3
(Kunming Medical University)
+ 5 AuthorsChen Qing12
Estimated H-index: 12
(Kunming Medical University)
Objective To investigate the anti-tumor effects and the mechanism of the compound 13-chlorine-3, 15-dioxy-gibberellic acid methyl ester (GA-13315) in lung adenocarcinoma in vitro and in vivo.
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