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Averting a malaria disaster: will insecticide resistance derail malaria control?

Published on Apr 1, 2016in The Lancet59.10
· DOI :10.1016/S0140-6736(15)00417-1
Janet Hemingway69
Estimated H-index: 69
(LSTM: Liverpool School of Tropical Medicine),
Hilary Ranson65
Estimated H-index: 65
(LSTM: Liverpool School of Tropical Medicine)
+ 12 AuthorsNicholas Hamon3
Estimated H-index: 3
Abstract
Summary World Malaria Day 2015 highlighted the progress made in the development of new methods of prevention (vaccines and insecticides) and treatment (single dose drugs) of the disease. However, increasing drug and insecticide resistance threatens the successes made with existing methods. Insecticide resistance has decreased the efficacy of the most commonly used insecticide class of pyrethroids. This decreased efficacy has increased mosquito survival, which is a prelude to rising incidence of malaria and fatalities. Despite intensive research efforts, new insecticides will not reach the market for at least 5 years. Elimination of malaria is not possible without effective mosquito control. Therefore, to combat the threat of resistance, key stakeholders need to rapidly embrace a multifaceted approach including a reduction in the cost of bringing new resistance management methods to market and the streamlining of associated development, policy, and implementation pathways to counter this looming public health catastrophe.
  • References (17)
  • Citations (107)
References17
Newest
#1Edward K. Thomsen (LSTM: Liverpool School of Tropical Medicine)H-Index: 10
#2Clare Strode (LSTM: Liverpool School of Tropical Medicine)H-Index: 19
Last.Javan ChandaH-Index: 1
view all 17 authors...
#1Clare Strode (Edge Hill University)H-Index: 19
#2Sarah Donegan (LSTM: Liverpool School of Tropical Medicine)H-Index: 19
Last.Janet Hemingway (LSTM: Liverpool School of Tropical Medicine)H-Index: 69
view all 5 authors...
#1Eric Ochomo (Kenya Medical Research Institute)H-Index: 10
#2Nabie Bayoh (Kenya Medical Research Institute)H-Index: 16
Last.John E. Gimnig (CDC: Centers for Disease Control and Prevention)H-Index: 36
view all 10 authors...
#1Stephen S Lim (UW: University of Washington)H-Index: 62
#2Nancy Fullman (UW: University of Washington)H-Index: 32
Last.Emmanuela Gakidou (UW: University of Washington)H-Index: 52
view all 7 authors...
#1Janet Hemingway (LSTM: Liverpool School of Tropical Medicine)H-Index: 69
#2Barry J. Beaty (CSU: Colorado State University)H-Index: 52
Last.Brian Sharp (Medical Research Council)H-Index: 27
view all 5 authors...
Cited By107
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#1Catherine L. Moyes (University of Oxford)H-Index: 27
#2Antoinette Wiebe (University of Oxford)H-Index: 7
Last.Eric Ochomo (Kenya Medical Research Institute)H-Index: 10
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#1Nadège Gouignard (NYU: New York University)
#2Floriane Cherrier (French Institute of Health and Medical Research)H-Index: 1
Last.Christian Mitri (Pasteur Institute)H-Index: 8
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#1Daisuke S. Yamamoto (Jichi Medical University)H-Index: 7
#2Megumi Sumitani (National Agriculture and Food Research Organization)H-Index: 8
Last.Hirotomo Kato (Jichi Medical University)H-Index: 23
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#1Margaux Mulatier (CNRS: Centre national de la recherche scientifique)
#2Cédric Pennetier (CNRS: Centre national de la recherche scientifique)H-Index: 3
Last.Anna CohuetH-Index: 26
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