A potent alpha-glucosidase inhibitor from Myristica cinnamomea King
Abstract
A dimeric acylphenol and a potent α-glucosidase inhibitor, giganteone D (IC50 5.05 μM), was isolated and characterized from the bark of Myristica cinnamomea King. The bark also yielded an acylphenol with an unprecedented skeleton for which the name cinnamomeone A (IC50 358.80 μM) was proposed. Their structures were established by means of NMR and MS spectrometric analyses. The Lineweaver–Burk plot of giganteone D indicated that it was a...
Paper Details
Title
A potent alpha-glucosidase inhibitor from Myristica cinnamomea King
Published Date
Feb 1, 2016
Journal
Volume
122
Pages
265 - 269
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History