Characterization of changes in plasma and tissue oxylipin levels in LPS and CLP induced murine sepsis
Abstract
The present study aimed to comprehensively investigate the changes in oxylipins during murine sepsis induced by lipopolysaccharide (LPS) or cecal ligation and puncture (CLP). Twenty-four hours after induction of sepsis in male C57BL/6 mice by LPS or CLP, plasma and liver, lung, kidney and heart tissues were sampled. Oxylipin levels in plasma and tissue were quantified by means of LC–MS. Moreover, clinical chemistry parameters were determined in...
Paper Details
Title
Characterization of changes in plasma and tissue oxylipin levels in LPS and CLP induced murine sepsis
Published Date
Dec 8, 2015
Journal
Volume
65
Issue
2
Pages
133 - 142
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