Antiarrhythmic therapy in patients with atrial fibrillation

Summary Atrial fibrillation is the most frequent arrhythmia, that still remains one of the most diffficult to pharmacological management. Antiarrhythmic drugs have been widely used to restore sinus rhythm and to prevent reccurence of arrhythmia, but pharmacological therapy is limited to several available agents, because of insufficient efficiacy and the significant risk of serious adverse effects. In patients with atrial fibrillation without...