In situ vaccination with cowpea mosaic virus nanoparticles suppresses metastatic cancer
Abstract
Nanotechnology has tremendous potential to contribute to cancer immunotherapy. The ‘in situ vaccination’ immunotherapy strategy directly manipulates identified tumours to overcome local tumour-mediated immunosuppression and subsequently stimulates systemic antitumour immunity to treat metastases. We show that inhalation of self-assembling virus-like nanoparticles from cowpea mosaic virus (CPMV) reduces established B16F10 lung melanoma and...
Paper Details
Title
In situ vaccination with cowpea mosaic virus nanoparticles suppresses metastatic cancer
Published Date
Dec 21, 2015
Journal
Volume
11
Issue
3
Pages
295 - 303
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