Systemic mast cell disease associated with B-chronic lymphocytic leukemia.

Patients with systemic mastocytosis (SM) are at a high risk of developing life-threatening myeloid malignancies such as acute myeloid leukemia, chronic myeloid leukemia or myelomonocytic leukemia. Lymphoproliferative disorders may also occur, although more rarely. We report a case of a patient with SM who developed chronic lymphocytic leukemia ten years after the diagnosis of his original disease. To our knowledge, this is the first reported...