Novel Biomarker of Oxidative Stress Is Associated With Risk of Death in Patients With Coronary Artery Disease

Background— Free radical scavengers have failed to improve patient outcomes, promoting the concept that clinically important oxidative stress may be mediated by alternative mechanisms. We sought to examine the association of emerging aminothiol markers of nonf ree radical mediated oxidative stress with clinical outcomes. Methods and Results— Plasma levels of reduced (cyst ei ne and glutathione) and oxidized (cyst i ne and glutathione disulphide)...