A combined binary interaction and phenotypic map of C. elegans cell polarity proteins
Abstract
The establishment of cell polarity is an essential process for the development of multicellular organisms and the functioning of cells and tissues. Here, we combine large-scale protein interaction mapping with systematic phenotypic profiling to study the network of physical interactions that underlies polarity establishment and maintenance in the nematode Caenorhabditis elegans. Using a fragment-based yeast two-hybrid strategy, we identified 439...
Paper Details
Title
A combined binary interaction and phenotypic map of C. elegans cell polarity proteins
Published Date
Jan 18, 2016
Journal
Volume
18
Issue
3
Pages
337 - 346
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