Inferring the age of a fixed beneficial allele

Volume: 25, Issue: 1, Pages: 157 - 169
Published: Dec 24, 2015
Abstract
Estimating the age and strength of beneficial alleles is central to understanding how adaptation proceeds in response to changing environmental conditions. Several haplotype-based estimators exist for inferring the age of segregating beneficial mutations. Here, we develop an approximate Bayesian-based approach that rather estimates these parameters for fixed beneficial mutations in single populations. We integrate a range of existing diversity,...
Paper Details
Title
Inferring the age of a fixed beneficial allele
Published Date
Dec 24, 2015
Volume
25
Issue
1
Pages
157 - 169
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