The Proteome of Filter-Grown Caco-2 Cells With a Focus on Proteins Involved in Drug Disposition
Abstract
Caco-2 cells are widely used in studies of intestinal cell physiology and drug transport. Here, the global proteome of filter-grown Caco-2 cells was quantified using the total protein approach and compared with the human colon and jejunum proteomes. In total, 8096 proteins were identified. In-depth analysis of proteins defining enterocyte differentiation—including brush-border hydrolases, integrins, and adherens and tight junctions—gave...
Paper Details
Title
The Proteome of Filter-Grown Caco-2 Cells With a Focus on Proteins Involved in Drug Disposition
Published Date
Feb 1, 2016
Volume
105
Issue
2
Pages
817 - 827
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