Original paper

IL-33 amplifies an innate immune response in the degenerating retina

Volume: 213, Issue: 2, Pages: 189 - 207
Published: Jan 11, 2016
Abstract
Age-related macular degeneration (AMD), a leading cause of vision impairment in the ageing population, is characterized by irreversible loss of retinal pigment epithelial (RPE) cells and photoreceptors and can be associated with choroidal neovascularization. Mononuclear phagocytes are often present in AMD lesions, but the processes that direct myeloid cell recruitment remain unclear. Here, we identify IL-33 as a key regulator of inflammation and...
Paper Details
Title
IL-33 amplifies an innate immune response in the degenerating retina
Published Date
Jan 11, 2016
Volume
213
Issue
2
Pages
189 - 207
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