Molecular changes indicative of cartilage degeneration and osteoarthritis development in patients with anterior cruciate ligament injury
Abstract
Anterior cruciate ligament (ACL) tear is considered a risk factor for osteoarthritis development. The purpose of our study was to investigate the expression levels of the apoptotic enzyme caspase 3, pro-inflammatory cytokines interleukin-1β (IL-1β) and interleukin-6 (IL-6) and degrading enzyme matrix metalloproteinase 13 (MMP-13), all indicative of cartilage degeneration and osteoarthritis development in patients’ chondrocytes after ACL rupture....
Paper Details
Title
Molecular changes indicative of cartilage degeneration and osteoarthritis development in patients with anterior cruciate ligament injury
Published Date
Jan 13, 2016
Volume
17
Issue
1
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