Generation and Application of Mouse-Rat Allodiploid Embryonic Stem Cells

Cell64.50
Volume: 164, Issue: 1-2, Pages: 279 - 292
Published: Jan 1, 2016
Abstract
•The mouse-rat AdESCs are genetically stable and pluripotent•The AdESCs exhibit mid-parent and species-biased gene expression patterns•Mouse-specific X inactivation in allodiploid cells reveals Xi-escaping genes•The AdESCs provide a tool to study the species-specific pluripotency maintenance Mammalian interspecific hybrids provide unique advantages for mechanistic studies of speciation, gene expression regulation, and X chromosome inactivation...
Paper Details
Title
Generation and Application of Mouse-Rat Allodiploid Embryonic Stem Cells
Published Date
Jan 1, 2016
Journal
Volume
164
Issue
1-2
Pages
279 - 292
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