Human dendritic cells

Dendritic cells are the most potent antigen-presenting cells. They, only, can prime naive T lymphocytes. They can also elicit generation of cytotoxic T lymphocytes against viral or tumour antigens and regulate humoral immune responses. The current paradigm is that dendritic cells differentiate from bone marrow progenitors and migrate via the blood to be distributed to tissues ; these immature dendritic cells have the capacity to capture and...