White, brite, and brown adipocytes: the evolution and function of a heater organ in mammals
Abstract
Brown fat is a specialized heater organ in eutherian mammals. In contrast to the energy storage function of white adipocytes, brown adipocytes dissipate nutrient energy by uncoupling of mitochondrial oxidative phosphorylation, which depends on uncoupling protein 1 (UCP1). UCP1, as well as UCP2 and UCP3, belong to the family of mitochondrial carriers inserted into the inner mitochondrial membrane for metabolite trafficking between the matrix and...
Paper Details
Title
White, brite, and brown adipocytes: the evolution and function of a heater organ in mammals
Published Date
Jul 1, 2014
Journal
Volume
92
Issue
7
Pages
615 - 626
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