A-Raf: A new star of the family of raf kinases

Volume: 50, Issue: 6, Pages: 520 - 531
Published: Oct 27, 2015
Abstract
The Ras-Raf-MEK-MAPK (mitogen-activated protein kinase)-signaling pathway plays a key role in the regulation of many cellular functions, including cell proliferation, differentiation and transformation, by transmitting signals from membrane receptors to various cytoplasmic and nuclear targets. One of the key components of this pathway is the serine/threonine protein kinase, Raf. The Raf family kinases (A-Raf, B-Raf and C-Raf) have been...
Paper Details
Title
A-Raf: A new star of the family of raf kinases
Published Date
Oct 27, 2015
Volume
50
Issue
6
Pages
520 - 531
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