Abstract P5-11-01: Correlation of the effects of potential and known chemopreventive agents on proliferation rates in normal mammary glands and mammary cancers with their chemopreventive efficacy

Volume: 75
Published: May 1, 2015
Abstract
Core needle biopsy, fine needle aspiration, or imaging (e.g., mammography) are currently used to examine chemopreventive agent efficacy in Phase II breast cancer trials. However, biomarker endpoints, such as proliferation rates using Ki67 in null or null risk breast tissue, have not been formally validated relative to cancer outcome. The aim of this study was to validate Ki-67 in normal mammary tissue from the methylnitrosourea (MNU) rat mammary...
Paper Details
Title
Abstract P5-11-01: Correlation of the effects of potential and known chemopreventive agents on proliferation rates in normal mammary glands and mammary cancers with their chemopreventive efficacy
Published Date
May 1, 2015
Volume
75
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