Evacetrapib alone or in combination with statins lowers lipoprotein(a) and total and small LDL particle concentrations in mildly hypercholesterolemic patients

•Evacetrapib 100-mg monotherapy-lowered Lp(a) concentrations by 32%. •Evacetrapib 100 mg with a statin-lowered Lp(a) concentrations by 31%. •Evacetrapib 100-mg monotherapy-lowered sLDL particle concentrations by 84%. •Evacetrapib 100 mg with a statin-lowered sLDL particle concentrations by 60%. •Statin monotherapy had no effect on Lp(a) and sLDL particle concentrations. Background Potent CETP inhibitors reduce plasma concentrations of...