DAT imaging and clinical biomarkers in relatives at genetic risk for LRRK2 R1441G Parkinson's disease
Abstract
Background
The objective of this study was to study motor and nonmotor symptoms and striatal dopaminergic denervation, as well as the relationship between them, in a cohort of asymptomatic relatives of patients with Parkinson's disease (PD) with the R1441G-leucine-rich repeat kinase 2 mutation.
Methods
Asymptomatic relatives of patients with PD and this mutation were tested for the presence of the mutation and evaluated for...
Paper Details
Title
DAT imaging and clinical biomarkers in relatives at genetic risk for LRRK2 R1441G Parkinson's disease
Published Date
Mar 1, 2016
Journal
Volume
31
Issue
3
Pages
335 - 343
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Notes
History