DAMP and DIC: The role of extracellular DNA and DNA-binding proteins in the pathogenesis of DIC
Abstract
Disseminated intravascular coagulation (DIC) is a heterogeneous group of disorders, which manifest as a spectrum of haemorrhage and thrombosis complicating many primary conditions including sepsis, trauma and malignancies. The pathophysiology of this condition is complex. In the recent years there is growing evidence that damage associated molecular patterns (DAMPs) play a crucial role in the pathogenesis of DIC. Upon cell-death and/or cell...
Paper Details
Title
DAMP and DIC: The role of extracellular DNA and DNA-binding proteins in the pathogenesis of DIC
Published Date
Jul 1, 2016
Journal
Volume
30
Issue
4
Pages
257 - 261
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Notes
History