The TLR2 is activated by sporozoites and suppresses intrahepatic rodent malaria parasite development.
Abstract
TLRs (Toll-like receptors) play an important role in the initiation of innate immune responses against invading microorganisms. Although several TLRs have been reported to be involved in the innate immune response against the blood-stage of malaria parasites, the role of TLRs in the development of the pre-erythrocytic stage is still largely unknown. Here, we found that sporozoite and its lysate could significantly activate the TLR2, and induce...
Paper Details
Title
The TLR2 is activated by sporozoites and suppresses intrahepatic rodent malaria parasite development.
Published Date
Dec 15, 2015
Journal
Volume
5
Issue
1
Pages
18239 - 18239
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Notes
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