Minireview: CNS Mechanisms of Leptin Action
Abstract
Leptin is an adipocytokine that circulates in proportion to body fat to signal the repletion of long-term energy stores. Leptin acts via its receptor, LepRb, on specialized neuronal populations in the brain (mainly in the hypothalamus and brainstem) to alter motivation and satiety, as well as to permit energy expenditure and appropriate glucose homeostasis. Decreased leptin, as with prolonged caloric restriction, promotes a powerful orexigenic...
Paper Details
Title
Minireview: CNS Mechanisms of Leptin Action
Published Date
Jan 1, 2016
Journal
Volume
30
Issue
1
Pages
3 - 12
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