ID: 73: Type I interferon-associated signaling in T cells: The novel functions of STING
Abstract
The cytoplasmic protein Stimulator of Interferon Genes (STING) plays an essential role in sensing cytoplasmic DNA of intracellular pathogens and initiating IFN type I responses in myeloid cells. It can also directly bind cyclic dinucleotides produced by intracellular bacteria or by the DNA-binding cyclic GMP-AMP (cGAMP) synthase. To date, the signaling mechanisms involving STING activation has been studied in macrophages and dendritic cells....
Paper Details
Title
ID: 73: Type I interferon-associated signaling in T cells: The novel functions of STING
Published Date
Nov 1, 2015
Journal
Volume
76
Issue
1
Pages
78 - 79
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Notes
History