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Cymbopogon citratus (DC.) Stapf : ethnopharmacologie, phytochimie, activités pharmacologiques et toxicologie

Published on Dec 1, 2016in Sozial-und Praventivmedizin
· DOI :10.1007/s10298-015-1014-3
N’goran Mathieu Kouame1
Estimated H-index: 1
(UCA: Université Félix Houphouët-Boigny),
M. Kamagate1
Estimated H-index: 1
(UCA: Université Félix Houphouët-Boigny)
+ 3 AuthorsA. Kakou1
Estimated H-index: 1
(UCA: Université Félix Houphouët-Boigny)
Abstract
Cymbopogon citratus (DC.) Stapf est une herbe aromatique vivace appartenant a la famille des Poaceae (Graminees), utilisee traditionnellement pour soigner diverses maladies. De nombreuses etudes ont montre que cette plante possede des proprietes antimicrobiennes, antifongiques, antiinflammatoires, anti-oxydantes, anti-cancerigenes, antidiabetiques, cardiovasculaires, insecticides et antiparasitaires. Les molecules les plus importantes responsables de ses proprietes therapeutiques sont: citral, myrcene, limonene, tanins, acetate de nerol, acetate de neryl, linalool, acetate de geranyl, terpinene-4-ol, β-caryophyllene, geraniol, saponosides, composes phenoliques, flavonoides. Bien que les extraits du C. citratus ou certains de ses constituants tels que le citral, le myrcene et le limonene soient toxiques a forte dose, aucun cas d’intoxication relatif a l’utilisation du C. citratus n’a ete decrit dans la litterature. Cet article est un resume non-exhaustif de la description botanique, de l’ethnopharmacologie, de la phytochimie, de l’activite pharmacologique et de la toxicite du C. citratus.
  • References (95)
  • Citations (1)
References95
Newest
#1V Francisco (UC: University of Coimbra)H-Index: 10
#2Gustavo Costa (UC: University of Coimbra)H-Index: 10
Last. Maria Teresa Batista (UC: University of Coimbra)H-Index: 20
view all 10 authors...
Abstract Ethnopharmacological relevance Cymbopogon citratus (DC.) Stapf leaves infusion is used in traditional medicine for the treatment of inflammatory conditions, however little is known about their bioactive compounds. Aim of the study Investigate the compounds responsible for anti-inflammatory potential of Cymbopogon citratus (Cy) on cytokines production induced by lipopolysaccharide (LPS) in human and mouse macrophages, and the action mechanisms involved. Materials and methods An essential...
53 CitationsSource
#1Thales Leandro Coutinho de Oliveira (State University of Campinas)H-Index: 9
Last. Roberta Hilsdorf PiccoliH-Index: 18
view all 3 authors...
Abstract The antimicrobial effect of oregano ( Origanum vulgare L.) and lemongrass ( Cymbopogon citratus (DC.) Stapf.) essential oils (EOs) against Salmonella enterica serotype Enteritidis in in vitro experiments, and inoculated in ground bovine meat during refrigerated storage (4 ± 2 °C) for 6 days was evaluated. The Weibull model was tested to fit survival/inactivation bacterial curves (estimating of p and δ parameters). The minimum inhibitory concentration ( MIC ) value for both EOs on S. Ent...
32 CitationsSource
#1Shanoo Suroowan (UoM: University of Mauritius)H-Index: 6
#2Fawzi M. Mahomoodally (UoM: University of Mauritius)H-Index: 11
Abstract Objective To assess CAM usage among women in Mauritius. Methods Cross-sectional survey with a nationally-representative sample ( n = 384). Quantitative indices included informant-consensus factor, use-value, fidelity-value and use-mentions were calculated. Results Thirteen therapies were identified and currently are used to treat or manage 26 ailments. These were phytotherapy (30%); yoga (13%); deep-breathing (12%); massage therapy (11%); ayurvedic medicine (8%); meditation (6%); zoothe...
17 CitationsSource
#1J. D. GbenouH-Index: 5
#2Judith F. AhounouH-Index: 1
Last. Simeon O. Kotchoni (RU: Rutgers University)H-Index: 22
view all 11 authors...
Cymbopogon citratus and Eucalyptus citriodora are widely used herbs/plants as a source of ethnomedicines in tropical regions of the world. In this work, we studied the anti-inflammatory and gastroprotective effects of C. citratus and E. citriodora essential oils on formol-induced edema, and acetic acid induced abdominal cramps in Wistar rats. To fully understand the chemically induced anti-inflammatory properties of these plants, we first analyzed the chemical composition of the essential oils. ...
47 CitationsSource
#1I. Precious Dike (Covenant University)H-Index: 1
#2Olawole O. Obembe (Covenant University)H-Index: 9
Last. F. Ezekiel Adebiyi (Covenant University)H-Index: 1
view all 3 authors...
Abstract Aim of study The ethnobotanical study surveyed the different types of medicinal plants used for the treatment of malaria in the south-western region of Nigeria. Materials and methods Information was collected by interviewing indigenous people, using a semi-structured questionnaire. Collected plant samples were identified and authenticated in Forestry Research Institute of Nigeria, Ibadan, Nigeria. Results A total of 151 respondents were interviewed of which 64% were females and 36% male...
42 CitationsSource
#1Rhuan Amorim Ritter (UFPA: Federal University of Pará)H-Index: 2
#2Maria Vivina Barros Monteiro (UFPA: Federal University of Pará)H-Index: 7
view all 10 authors...
Abstract Ethnopharmacological relevance The lack of ethnoveterinary surveys in Brazil, especially in the Amazon region, results in losses in the veterinary phytopharmacology field and in scientific documentation of the cultural traditions of plant use in the treatment of animal diseases. Aim of the study To catalog, analyze and disseminate the ethnoveterinary knowledge of the inhabitants of Colares Island, Para state, eastern Amazon, Brazil. Materials and methods A total of 72 interviews were co...
22 CitationsSource
#1Priscila Ikeda Ushimaru (UNESP: Sao Paulo State University)H-Index: 5
#2Lidiane Nunes Barbosa (UNESP: Sao Paulo State University)H-Index: 11
Last. A. Fernandes Junior (UNESP: Sao Paulo State University)H-Index: 9
view all 5 authors...
The biological properties of medicinal plants have been documented worldwide for many centuries. We aimed to evaluate interactions between crude extracts from Psidium guajava, Zingiber officinale, Cymbopogon citratus, Caryophyllus aromaticus, Mikania glomerata and Allium sativum samples and antimicrobial drugs against Escherichia coli strains. The susceptibility test performed was disc diffusion, and crude extracts were diluted (%v/v) into Muller–Hinton agar (MHA) at one quarter of the minimal i...
14 CitationsSource
#1R. Chitra DeviH-Index: 1
#2Si Mui SimH-Index: 18
Last. Rosnah Ismail (UM: University of Malaya)H-Index: 3
view all 3 authors...
Cymbopogon citratus has been shown to have antioxidant, antimicrobial, antispasmodic and chemo-protective properties. Citral, is the major constituent of C. citratus. This study investigated the effects of methanolic extracts of leaves (LE), stems (SE), and roots (RE) of C. citratus and citral on vascular smooth muscle and explored their possible mechanisms of action. The experiment was conducted using isolated tissue preparations, where citral, LE, SE, and RE were added separately into a tissue...
20 CitationsSource
#1Marisa Machado (UC: University of Coimbra)H-Index: 8
#2P. Pires (UC: University of Coimbra)H-Index: 1
Last. Maria do Céu Sousa (UC: University of Coimbra)H-Index: 11
view all 8 authors...
Abstract In order to contribute for the search of new drugs for leishmaniasis, we study the susceptibility of Leishmania infantum , Leishmania tropica and Leishmania major to Cymbopogon citratus essential oil and major compounds, mrycene and citral. C . citratus and citral were the most active inhibiting L. infantum , L. tropica and L. major growth at IC 50 concentrations ranging from 25 to 52 μg/ml and from 34 to 42 μg/ml, respectively. L. infantum promastigotes exposed to essential oil and cit...
49 CitationsSource
Abstract Lemongrass (Cymbopogon citratus Stapf) essential oil has been used worldwide because of its ethnobotanical and medicinal usefulness. Regarding its medicinal usefulness, the present study evaluated the beneficial effects of lemongrass essential oil (LGEO) oral treatment on cell proliferation and apoptosis events and on early development of hyperplastic lesions in the mammary gland, colon, and urinary bladder induced by N-methyl-N-nitrosourea (MNU) in female BALB/c mice. The animals were ...
9 CitationsSource
Cited By1
Newest
#1Kessiane B. Almeida (Federal Fluminense University)H-Index: 2
#2Aline de Souza Ramos (FIOCRUZ: Oswaldo Cruz Foundation)H-Index: 7
Last. Deborah Q. Falcão (UdeM: Université de Montréal)H-Index: 1
view all 10 authors...
Abstract This study aimed to optimize Cymbopogon citratus essential oil loaded into PLGA-nanoparticles by investigating the effect of processing variables (sonication time, ultrasound power, and essential oil/polymer ratio) on encapsulation efficiency and particle mean hydrodynamic diameter using Box-Behnken design. Nanoparticles were prepared by an emulsification/solvent diffusion method and physicochemically characterized by FTIR, DSC and TGA/DTA. Cytotoxicity was evaluated in human HaCat kera...
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